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  • Title: In vitro and bactericidal activities of ABT-492, a novel fluoroquinolone, against Gram-positive and Gram-negative organisms.
    Author: Almer LS, Hoffrage JB, Keller EL, Flamm RK, Shortridge VD.
    Journal: Antimicrob Agents Chemother; 2004 Jul; 48(7):2771-7. PubMed ID: 15215148.
    Abstract:
    In vitro activities of ABT-492, ciprofloxacin, levofloxacin, trovafloxacin, moxifloxacin, gatifloxacin, and gemifloxacin were compared. ABT-492 was more potent against quinolone-susceptible and -resistant gram-positive organisms, had activity similar to that of ciprofloxacin against certain members of the family Enterobacteriaceae, and had comparable activity against quinolone-susceptible, nonfermentative, gram-negative organisms. Bactericidal activity of ABT-492 was also evaluated.
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