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  • Title: Acute myocardial infarction: tissue characterization with T1rho-weighted MR imaging--initial experience.
    Author: Muthupillai R, Flamm SD, Wilson JM, Pettigrew RI, Dixon WT.
    Journal: Radiology; 2004 Aug; 232(2):606-10. PubMed ID: 15215547.
    Abstract:
    Acute myocardial injury was evaluated in 21 patients by using a contrast material-enhanced T1rho-weighted cine turbo field-echo magnetic resonance (MR) imaging sequence and a delayed-enhancement sequence. In 12 of 21 patients, conventional T1-weighted contrast-enhanced cine turbo field-echo MR images were also collected for direct comparison with T1rho-weighted images. Delayed-enhancement technique distinctly characterized irreversible injury (percentage enhancement, 588% +/- 344). With T1rho weighting, percentage enhancement of irreversibly injured myocardium was 68% +/- 41, compared with 23% +/- 24 without T1rho weighting (P <.006). The addition of T1rho weighting to contrast-enhanced cine turbo field-echo MR sequences may offer a new contrast enhancement mechanism for characterization of acutely infarcted myocardium.
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