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  • Title: Design of diversity and focused combinatorial libraries in drug discovery.
    Author: Young SS, Ge N.
    Journal: Curr Opin Drug Discov Devel; 2004 May; 7(3):318-24. PubMed ID: 15216935.
    Abstract:
    Using well-characterized chemical reactions and readily available monomers, chemists are able to create sets of compounds, termed libraries, which are useful in drug discovery processes. The design of combinatorial chemical libraries can be complex and there has been much information recently published offering suggestions on how the design process can be carried out. This review focuses on literature with the goal of organizing current thinking. At this point in time, it is clear that benchmarking of current suggested methods is required as opposed to further new methods.
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