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  • Title: Concomitant keratoconus and macular corneal dystrophy.
    Author: Javadi MA, Rafee'i AB, Kamalian N, Karimian F, Ja'farinasab MR, Yazdani S.
    Journal: Cornea; 2004 Jul; 23(5):508-12. PubMed ID: 15220737.
    Abstract:
    OBJECTIVE: To report the concomitant presentation of keratoconus and macular corneal dystrophy in two cases. METHODS: Two siblings with concomitant keratoconus and macular corneal dystrophy are presented. Complete ophthalmologic examination and computerized videokeratography were performed in both patients. Case 1 underwent penetrating keratoplasty in both eyes sequentially; histopathologic examination of excised corneal buttons with special stains was performed. Case 2 was observed. RESULTS: Both patients manifested typical signs and topographic evidence of keratoconus associated with macular dystrophy. Histopathologic studies in case 1 confirmed the same clinical diagnosis. CONCLUSION: To our knowledge, this is the first report of such a concurrence in the English literature and could lead to further studies on the possible pathophysiologic or genetic link between these 2 entities.
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