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  • Title: Combined directed ortho and remote metalation-cross-coupling strategies. General method for benzo[a]carbazoles and the synthesis of an unnamed indolo[2,3-a]carbazole alkaloid.
    Author: Cai X, Snieckus V.
    Journal: Org Lett; 2004 Jul 08; 6(14):2293-5. PubMed ID: 15228262.
    Abstract:
    [reaction: see text] An efficient route to benzo[a]carbazoles via a metalation-cross-coupling sequence has been demonstrated and its application to the synthesis of the antitumor and antiviral alkaloid 6-cyano-5-methoxy-12-methylindolo[2,3-a]carbazole has been achieved.
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