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  • Title: [Pharmacotherapy of acute tonsillitis-pharyngitis in ambulatory practice: results of a multicenter pharmaco-epidemiological study].
    Author: Kozlov SN, Strachunskiĭ LS, Rachina SA, Dmitrenok OV, Iliushchenko LA, Kuzin VB, Ortenberg EA, Paliutin ShKh, Sosonnaia NA.
    Journal: Ter Arkh; 2004; 76(5):45-51. PubMed ID: 15230132.
    Abstract:
    AIM: To analyse current practice of pharmacotherapy (PT) in outpatient treatment of acute tonsillopharyngitis (ATP) in different regions of Russia. MATERIAL AND METHODS: Case reports for 1333 outpatients (493 male and 840 female, age 16-76 years) with ATP from 7 cities of Russia have been studied. Each ATP case was documented on a special chart to contain the following information: demographic data, history of the disease, bacteriological findings, PT regimens, complications, treatment outcomes. RESULTS: PT of ATP was made primarily with antibiotics. Most frequent of them was ampicillin (about half the cases). Further antibiotics by frequency of use were: erythromycin, ciprofloxacin, doxicyclin, amoxicillin, midecamycin, ampicillin/oxacillin. Among other drugs, wide use was registered of antihistamine drugs, throat disease drugs, analgetic and antipiretic drugs, vitamins. Bacteriological examinations were conducted rarely. CONCLUSION: The problems of PT of ATP patients consist in overuse of systemic antibiotics as a result of adequate differential diagnosis of this infection and choice of antibiotics without consideration of current recommendations on the treatment of streptococcal ATP.
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