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  • Title: Simplified surgical placement and stabilization methods for intracerebroventricular cannulas in rat lateral ventricles.
    Author: Jho DH, Engelhard HH, Juarez A, Espat NJ.
    Journal: Lab Anim (NY); 2003 Oct; 32(9):43-8. PubMed ID: 15235663.
    Abstract:
    Intracerebroventricular cannulation in rat models is an efficient tool for exploring the effects of substances directly injected into the CNS, bypassing the blood-brain barrier. Techniques for surgically securing the ICV cannula require a balance between ease of application and adequate stability. The authors tested several methods of lateral ventricle cannula stabilization, especially focusing on a comparison of cyanoacrylate gel to cranioplastic cement with an anchoring bone screw.
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