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Title: [Surgical treatment for temporal lobe epilepsy in patients over age 50 years]. Author: Morioka T, Hashiguchi K, Fukui K, Kawamura T, Sasaki M, Mihara F, Sasaki T. Journal: No To Shinkei; 2004 Apr; 56(4):326-32. PubMed ID: 15237724. Abstract: We retrospectively analyzed 4 patients over age 50 (52 - 57) years with intractable medial temporal lobe epilepsy(MTLE) who underwent the anterior temporal lobectomy with hippocampectomy. Case 1 had MTLE with old brain abscess in the left lateral temporal lobe and Cases 2 - 4 had MTLE with histologically verified hippocampal sclerosis. In Cases 2 - 4, although the onset of seizures occurred 26 to 37 years prior to the time of surgery, there was no mental problem (IQ = 87 - 100). In Cases 1, chronic invasive electrocorticography recording using subdural electrodes was obtained, while in Case 2 - 4, the epileptogenic region was defined by noninvasive preoperative evaluation. Postoperatively, all patients obtained a meaningful improvement, becoming either free from seizures or only experiencing a rare seizure, and returned to work or usual activities without surgical complications. Surgery for MTLE appears to be effective for older individuals and carries a small risk of postoperative complications.[Abstract] [Full Text] [Related] [New Search]