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  • Title: Iridium-192 interstitial brachytherapy as adjunctive treatment for canine cutaneous mast cell tumors.
    Author: Northrup NC, Roberts RE, Harrell TW, Allen KL, Howerth EW, Gieger TL.
    Journal: J Am Anim Hosp Assoc; 2004; 40(4):309-15. PubMed ID: 15238561.
    Abstract:
    Eleven dogs with cutaneous mast cell tumors (MCTs) were treated with surgery and iridium-192 ((192)Ir) interstitial brachytherapy. Minimum tumor doses ranged from 47.2 to 63.3 Gy. Treated tumors were classified as grade II (n=7) or III (n=4). Five dogs had recurrences with a median progression-free interval of 1391 days, and six dogs had no recurrence at a median follow-up time of 942 days. Acute adverse effects were well tolerated, and late effects were mild. One dog developed a second tumor of a different cell type in the radiation treatment field.
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