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  • Title: Erectile and urinary dysfunction after radical prostatectomy for prostate cancer in Quebec: a population-based study of 2415 men.
    Author: Karakiewicz PI, Tanguay S, Kattan MW, Elhilali MM, Aprikian AG.
    Journal: Eur Urol; 2004 Aug; 46(2):188-94. PubMed ID: 15245812.
    Abstract:
    OBJECTIVE: To assess and quantify urinary and sexual function outcomes from a large scale cohort of Canadian men treated for localized prostate cancer. METHODS: A self-administered survey focusing on erectile (ED) and urinary dysfunction (UD) was completed by 2415 of 4546 men (response rate 53.1%) treated with prostatectomy for prostate cancer in the Province of Quebec between 1988 and 1996. The time between treatment and survey completion ranged from 17 months to 8.5 years. RESULTS: After prostatectomy, of 2227 men without ED before surgery, erections of adequate firmness for intercourse were reported by 25%. ED rate increased with age and ranged from 55% in men aged <60 years to 85% in men 75 years or older. Of all, 19.1% reported ED treatment. ED rate was significantly related to UD severity. Severe UD, quantified as urinary leakage exceeding one tablespoon, was reported by 6.6%. Severe UD rate ranged from 4% in men aged <60 years to 10% in men 75 years or older. Strictures were reported by 16.3% and were associated with a two-fold increase in severe UD rate (p<0.001). Finally, age and socioeconomic status represented important predictor variables in univariate and multivariate regression models. CONCLUSION: ED rate of 75% and severe UD rate of 6.6% could be anticipated after RP. These outcomes are similar to unselected large scale, patient reported outcomes from the United States.
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