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  • Title: Prognostic importance of renal function in patients with early heart failure and mild left ventricular dysfunction.
    Author: Smilde TD, Hillege HL, Voors AA, Dunselman PH, Van Veldhuisen DJ.
    Journal: Am J Cardiol; 2004 Jul 15; 94(2):240-3. PubMed ID: 15246913.
    Abstract:
    We evaluated the prognostic value of renal function in an initially "untreated" population with mild heart failure and compared the prognosis of this population with a matched controlled population. During a follow-up of 13 years (mean 11.7), 90 patients (56%) died. Mortality was higher compared with a matched controlled population. Multivariate Cox regression analysis demonstrated that beside the well-established risk markers of left ventricular ejection fraction and heart rate, renal function (estimated glomerular filtration rate, hazard ratio 1.16/10 ml/min/1.73 m(2), p = 0.003) was the only additional independent predictor of cardiovascular mortality in patients with early heart failure.
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