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  • Title: Vascular hemichorea/hemiballism and topiramate.
    Author: Gatto EM, Uribe Roca C, Raina G, Gorja M, Folgar S, Micheli FE.
    Journal: Mov Disord; 2004 Jul; 19(7):836-838. PubMed ID: 15254947.
    Abstract:
    Although vascular hemichorea/hemiballism (HC/HB) has been reported to be self-limited, in some cases, it can be irreversible and severely disabling. The standard treatment includes typical and atypical neuroleptics and GABA-mimetic drugs. Topiramate is a new antiepileptic drug possessing a complex mechanism of action, including the enhancement of GABA-mediated inhibition. We describe a 71-year-old patient with HC/HB who markedly improved after topiramate treatment.
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