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  • Title: [Meningococcal disease due to Neisseria meningitidis serogroup W135 in children. Clinical aspects and outcome].
    Author: Faye A, Marianni-Kurkdjian P, Taha MK, Soussan V, Bingen E, Bourrillon A.
    Journal: Presse Med; 2004 Jun 05; 33(10):654-7. PubMed ID: 15257237.
    Abstract:
    OBJECTIVE: Meningococcal disease due to Neisseria meningitidis of serogroup W135 (N. meningitidis W135) is increasing in France. Clinical and outcome data concerning these infections in children are scarce. PATIENTS: We report 5 cases of children hospitalised in our unit between June 2000 and December 2002 for N. meningitidis W135 infection. CASE REPORTS: Among these 5 children aged 19 months to 11 years, 3 presented with a primary meningitis and 4 with primary or secondary extra-meningeal involvement, articular in 3 cases, pericardial in 2 cases and ocular in one case. The outcome was favourable without after effects in 4 cases, marked by a resistant prolonged post-meningococcal inflammatory syndrome. COMMENTS: Extra-meningeal septic and/or non septic complications are frequent and a prolonged post meningococcal inflammatory syndrome is reported. In N. meningitidis W135 infections a careful clinical evaluation of potential extra-meningeal complications and a long term follow up of children are needed.
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