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  • Title: Ultrastructure of vitreomacular traction syndrome associated with persistent hyaloid artery.
    Author: Gandorfer A, Rohleder M, Charteris D, Kampik A, Luthert P.
    Journal: Eye (Lond); 2005 Mar; 19(3):333-6. PubMed ID: 15258604.
    Abstract:
    AIM: To demonstrate the ultrastructure of vitreomacular traction associated with persistent hyaloid artery. METHODS: Pars plana vitrectomy was performed in a 66-year-old man with progressive vitreomacular traction associated with a persistent hyaloid artery. Epimacular tissue was peeled and processed for transmission electron microscopy. RESULTS: Ultrastructural analysis revealed multiple sheets of cellular and collagenous components. Myofibroblasts and newly formed collagen were the predominant features. Fibrous astrocytes, fibroblasts, macrophages, and basement membrane were also present. CONCLUSION: The cellular composition of the epimacular tissue and high cellular activity suggest that persistence of the hyaloid artery may contribute to the development of vitreomacular traction.
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