These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Pathological observations of Fructus Schisandrae polysaccharide on anti-tumor effects in S180-bearing mice].
    Author: Huang L, Chen L, Zhang Z.
    Journal: Zhong Yao Cai; 2004 Mar; 27(3):202-3. PubMed ID: 15272786.
    Abstract:
    OBJECTIVE: To study the effects of Fructus Schisandrae Polysaccharide (FSP) on anti-tumor in S180-bearing mice. METHODS: The transplantable carcinosarcoma model was established in S180-bearing mice by subcutaneous implantation. Tumor size and histopathological changes were observed under electron microscopy by HE staining after 8 days treatment. RESULTS: Morphological changes showed that slight cataplasia and apoptosis were induced by high concentration FSP, as well as the numbers of inflammatory cells in tumor were increased and tumor cells in infiltration areas around tumor cataplasised partly. These suggested that high concentration FSP can inhibit tumor growth lightly. In addition, high concentration FSP combined with cyclophosphamide can promote the effect of anti-tumor. CONCLUSIONS: FSP can inhibit tumor growth, this effect may be correlated with apoptosis and the activation of immunocytes, but not depend on killing tumor cells directly. In addition, high concentration FSP combined with cyclophosphamide can promote the capacity on anti-tumor in S180-bearing mice.
    [Abstract] [Full Text] [Related] [New Search]