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  • Title: High prevalence of the ermB gene among erythromycin-resistant streptococcus pneumoniae isolates in Germany during the winter of 2000-2001 and in vitro activity of telithromycin.
    Author: Kresken M, Henrichfreise B, Bagel S, Brauers J, Wiedemann B.
    Journal: Antimicrob Agents Chemother; 2004 Aug; 48(8):3193-5. PubMed ID: 15273149.
    Abstract:
    Of 595 isolates of Streptococcus pneumoniae from outpatients with respiratory tract infections, collected from 17 microbiology laboratories, 14.1% were resistant to erythromycin. Eighty-three erythromycin-resistant isolates were genetically analyzed, 83.1% of which harbored the ermB gene. Only four isolates (4.8%) harbored the mefA gene. Telithromycin exhibited potent activity against all isolates.
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