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  • Title: Two dimensional PNA/DNA arrays: estimating the helicity of unusual nucleic acid polymers.
    Author: Lukeman PS, Mittal AC, Seeman NC.
    Journal: Chem Commun (Camb); 2004 Aug 07; (15):1694-5. PubMed ID: 15278141.
    Abstract:
    We extend the generality of nucleic acid-based structural nanotechnology by incorporating non-natural nucleic acids into a DNA double crossover (DX) molecule; visualizing two-dimensional arrays of these DX molecules by Atomic Force Microscopy (AFM) enables us to measure the helical repeat of any heteroduplex sequence capable of forming the outer arms of a DX.
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