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  • Title: Role of Arogh, a polyherbal formulation to mitigate oxidative stress in experimental myocardial infarction.
    Author: Suchalatha S, Thirugnanasambandam P, Maheswaran E, Shyamala Devi CS.
    Journal: Indian J Exp Biol; 2004 Feb; 42(2):224-6. PubMed ID: 15282960.
    Abstract:
    Antioxidant role of Arogh in isoproterenol induced myocardial infarction in rats has been studied. The activity of heart tissue antioxidants like glutathione, superoxide dismutase, catalase, glutathione peroxidase and glutathione-s-transferase were significantly decreased in isoproterenol administered group. The activity of ceruloplasmin and levels of glutathione, vitamins E and C were also found to be substantially decreased in serum with a concomitant rise in lipid peroxide levels after isoproterenol exposure to rats. The synergistic effect of Arogh pretreatment, significantly suppressed the alterations induced by isoproterenol alone in rats.
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