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  • Title: [Effect of propionate pathway metabolites on the oxidative activity of liver mitochondria under normal conditions and in vitamin B12 deficiency].
    Author: Gessler NN, Fedotcheva NI, Kondrashova MN, Bykhovskiĭ VIa.
    Journal: Prikl Biokhim Mikrobiol; 1992; 28(4):607-13. PubMed ID: 1528821.
    Abstract:
    We performed a comparative investigation in vivo and in vitro of the propionate and methylmalonate effect on oxidative activity of liver mitochondria in control and vitamin B12-deficient rats and found that efficiency of the effects were less pronounced in vitamin B12-deficient rats. It is also shown that the rates of respiration and phosphorylation decreased in liver mitochondria of vitamin B12-deficient rats.
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