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  • Title: Angiomyolipoma of the uterus associated with tuberous sclerosis: case report and review of the literature.
    Author: Cil AP, Haberal A, Hucumenoglu S, Kovalak EE, Gunes M.
    Journal: Gynecol Oncol; 2004 Aug; 94(2):593-6. PubMed ID: 15297212.
    Abstract:
    BACKGROUND: Angiomyolipoma (AML) is a rare benign tumor that occurs most commonly in the kidney. Only a few cases have been described in the uterus. CASE: We describe a 32-year-old woman with tuberous sclerosis who presented with irregular bleeding. Preoperatively, the lesions were confused with leiomyoma on ultrasound. At laparotomy, multiple circumscribed subserosal and intramural purplish lesions on the corpus uteri were noted leading to a diagnosis of uterine angiomyolipoma with the histological and immunohistochemical findings. CONCLUSION: In contrast to other reported uterine angiomyolipoma cases, HMB-45 melanoma-specific antibody immunoreactivity is demonstrated in the present case. The histopathologic diagnosis as well as immunohistochemical analysis is discussed here with a review of the literature.
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