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  • Title: Evaluation of a new automated, standardized generic nucleic acid extraction method (total nucleic acid isolation kit) used in combination with cytomegalovirus DNA quantification by COBAS AMPLICOR CMV MONITOR.
    Author: Gärtner BC, Fischinger JM, Litwicki A, Roemer K, Mueller-Lantzsch N.
    Journal: J Clin Microbiol; 2004 Aug; 42(8):3881-2. PubMed ID: 15297555.
    Abstract:
    The new generic Total Nucleic Acid Isolation kit improved the detection limit of a cytomegalovirus (CMV) PCR from 400 to 200 copies/ml. Sensitivity and specificity in 30 CMV-positive and 100 negative samples were 100%. Analytical performance was excellent. The kit provides a reliable, standardized, and time-saving tool for DNA extraction.
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