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  • Title: Gallbladder involvement of Henoch-Schönlein purpura mimicking acute acalculous cholecystitis.
    Author: Hoffmann JC, Cremer P, Preiss JC, Ebhardt H, Kruschewski M, Buhr HJ, Zeitz M.
    Journal: Digestion; 2004; 70(1):45-8. PubMed ID: 15297777.
    Abstract:
    BACKGROUND/AIMS: We report the case of a 53-year-old man with fever and severe abdominal pain following an upper respiratory tract infection. METHODS/RESULTS: The clinical signs, the laboratory markers, and the ultrasound findings were consistent with acute acalculous cholecystitis and he underwent cholecystectomy. Histologically the gallbladder showed vasculitis and the patient developed postoperatively a purpuric rash of the legs with transient ankle arthritis. Gastroscopy revealed prepyloric ulcers consistent with vasculitis. The patient was diagnosed as having Henoch-Schönlein purpura. Gastric ulcers as well as arthritis disappeared upon treatment with corticosteroids and proton pump inhibitors. CONCLUSION: Taken together, Henoch-Schönlein purpura can mimic acute cholecystitis and should be considered as a rare differential diagnosis of acute cholecystitis.
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