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  • Title: Improvement in behavioral symptoms and advance of activity acrophase after short-term bright light treatment in severe dementia.
    Author: Skjerve A, Holsten F, Aarsland D, Bjorvatn B, Nygaard HA, Johansen IM.
    Journal: Psychiatry Clin Neurosci; 2004 Aug; 58(4):343-7. PubMed ID: 15298644.
    Abstract:
    Ten elderly subjects with severe dementia were given bright light (5000-8000 lux) for 45 min each morning for 4 weeks. Two rating scales of behavioral symptoms in dementia were used as outcome measures: Cohen-Mansfield Agitation Inventory (CMAI) and Behavior Pathology In Alzheimer's Disease Rating Scale (BEHAVE-AD), a scale for sleep-wake disturbances, and actigraphy to monitor activity rhythm. Behavioral symptoms improved with treatment. No changes in sleep-wake measures were found. There was an advance of the activity rhythm acrophase during treatment. These results suggest that short-time bright light improves behavioral symptoms and aspects of activity rhythm disturbances even in severely demented subjects.
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