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  • Title: [Resistance of natural and synthetic polyribonucleotide inducers of interferon to human blood ribonucleases].
    Author: Surzhik MA, Diatlova NG, Glazunov EA, Timkovskiĭ AL, Vlasov GP, Kozhevnikova NIu.
    Journal: Antibiot Khimioter; 1992 Jan; 37(1):21-3. PubMed ID: 1530353.
    Abstract:
    The resistance of polyribonucleotide inductors of interferon to blood ribonucleases was studied. Blood resistance of larifan and ridostin in the free and shielded state as well as that of the complexes of poly(I)-poly(C) and poly(G)-poly(C) were also investigated. A protective action of polylysine against the inductors was detected which, in case it had no effect on the biological activity of the drugs, could provide its recommendation as a compound for shielding the inductors.
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