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  • Title: Asbestos-related pleural disease due to tremolite associated with progressive loss of lung function: serial observations in 123 miners, family members, and residents of Libby, Montana.
    Author: Whitehouse AC.
    Journal: Am J Ind Med; 2004 Sep; 46(3):219-25. PubMed ID: 15307120.
    Abstract:
    BACKGROUND: The community of Libby, Montana has recently been the focus of national attention secondary to widespread amphibole contamination associated with vermiculite mining and processing. METHODS: Patients who had occupational and non-occupational exposure to amphibole asbestos in Libby, Montana were evaluated for progressive loss of pulmonary function. RESULTS: Of the 123 patients evaluated, 94 demonstrated average age-corrected accelerated loss per year of vital capacity at 3.2%, total lung capacity (TLC) 2.3%, and DLCO 3.3%. All patients all had predominantly pleural changes with minimal to no interstitial disease. CONCLUSIONS: The study demonstrates a progressive loss of pulmonary function in patients exposed to tremolite asbestos.
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