These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Multiplexed colorimetric solid-phase extraction: determination of silver(I), nickel(II), and sample Ph.
    Author: Gazda DB, Fritz JS, Porter MD.
    Journal: Anal Chem; 2004 Aug 15; 76(16):4881-7. PubMed ID: 15307801.
    Abstract:
    This paper reports the design and ground-based testing of a multiplexed colorimetric solid-phase extraction (MC-SPE) platform for the rapid determination of multiple water quality parameters in a simple set of operational steps. Colorimetric solid-phase extraction (C-SPE) is an analytical platform that combines impregnated colorimetric reagents on a solid-phase extraction membrane and diffuse reflectance spectroscopy to quantify trace analytes in water. In extending C-SPE to MC-SPE, a filter holder that incorporates discrete analysis channels and a jig that facilitates the concurrent operation of multiple syringes have been designed, enabling the simultaneous determination of three different measures of water quality. Separate, single-parameter membranes, placed in a readout cartridge create unique, parameter-specific addresses at the exit of each channel. Following sample exposure, the diffuse reflectance spectrum of each address is collected serially and the Kubelka-Munk function is used to quantify each water quality parameter via calibration curves. Performance evaluations of the MC-SPE platform were conducted using sample pH, silver(I), and nickel(II). Determinations of silver(I) (0.05-0.5 ppm) and nickel(II) (1.8-5.0 ppm) follow established C-SPE methods on reversed-phase extraction membranes using 5-(p-dimethylaminobenzylidene)rhodanine and dimethylglyoxime, respectively, as colorimetric reagents. Sample pH (2.5-5.0) is measured using an anion-exchange membrane impregnated with fluorescein. These determinations require approximately 120 s to complete using a total sample volume of 3.0 mL. The extension of MC-SPE to the determination of a greater number of analytes and its potential application to space and earth-bound monitoring needs are briefly discussed.
    [Abstract] [Full Text] [Related] [New Search]