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  • Title: Pathogens resistant to antimicrobial agents: epidemiology, molecular mechanisms, and clinical management.
    Author: Kaye KS, Engemann JJ, Fraimow HS, Abrutyn E.
    Journal: Infect Dis Clin North Am; 2004 Sep; 18(3):467-511, viii. PubMed ID: 15308273.
    Abstract:
    Resistance to antimicrobial drugs is increasing at an alarming rate among both gram-positive and gram-negative bacteria. Traditionally, bacteria resistant to multiple antimicrobial agents have been restricted to the nosocomial environment. A disturbing trend has been the recent emergence and spread of resistant pathogens and resistance traits in nursing homes, the community, as well as in hospitals. This article reviews the epidemiology, molecular mechanisms of resistance, and treatment options for pathogens resistant to antimicrobial drugs.
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