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  • Title: Antibiotic sampling from central venous catheters versus peripheral veins.
    Author: McBeth CL, McDonald RJ, Hodge MB.
    Journal: Pediatr Nurs; 2004; 30(3):200-2. PubMed ID: 15311643.
    Abstract:
    This study was developed to determine if there are statistically or clinically significant differences in antibiotic levels of blood samples obtained from a central venous catheter (CVC) versus a peripheral vein. Currently there is limited and contradictory information comparing aminoglycoside levels drawn from a central line used for antibiotic infusions versus a separate peripheral blood draw. In this study antibiotic levels drawn from a central line were compared with levels drawn simultaneously from a peripheral vein. Significant clinical and statistical differences were identified based on the type of central catheter in place.
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