These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Synthesis of analogue structures of the p-quinone methide moiety of kendomycin.
    Author: Green MP, Pichlmair S, Marques MM, Martin HJ, Diwald O, Berger T, Mulzer J.
    Journal: Org Lett; 2004 Sep 02; 6(18):3131-4. PubMed ID: 15330605.
    Abstract:
    [reaction: see text] The synthesis of two model p-quinone methide ring systems of the antibiotic and antiosteoporotic compound kendomycin is reported. Two approaches were examined in detail, and the two-step (i) demethylation and (ii) DMDO oxidation were found to be reliable and generally applicable. Additionally, it was found that oxidation of a benzofuran by NaIO(4) on silica produced a long-lived semiquinone radical.
    [Abstract] [Full Text] [Related] [New Search]