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Title: Atypical teratoid/rhabdoid tumour with leptomeningeal dissemination in an adult. Author: Kawaguchi T, Kumabe T, Watanabe M, Tominaga T. Journal: Acta Neurochir (Wien); 2004 Sep; 146(9):1033-8; discussion 1038. PubMed ID: 15340816. Abstract: A 22-year-old man presented with a rare case of atypical teratoid/rhabdoid tumour (AT/RT). Magnetic resonance imaging showed a left cerebellar mass with leptomeningeal dissemination. Partial resection was performed. Histological examination revealed AT/RT. Postoperatively, whole neuraxis and local irradiation were performed. Three-drug chemotherapy with ifosfamide, cisplatin, and etoposide, and adjuvant intrathecal administration of methotrexate were repeated. Near complete response was achieved, and no tumour recurrence/progression has been noticed during the follow up of 24 months. Intensive radiochemotherapy can successfully control AT/RT, even with leptomeningeal dissemination.[Abstract] [Full Text] [Related] [New Search]