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  • Title: [Familial amyotrophic lateral sclerosis associated with Huntington chorea with increased aspartate level in the cerebrospinal fluid].
    Author: Blin O, Samuel D, Guieu R, Pouget J, Nieoullon A, Serratrice G.
    Journal: Rev Neurol (Paris); 1992; 148(2):144-6. PubMed ID: 1534926.
    Abstract:
    We report the case of a patient who presented with both amyotrophic lateral sclerosis and Huntington's disease. Interestingly, aspartate level was increased in the lumbar CSF. In vitro and in vivo studies have convincingly suggested that these two neurodegenerative diseases could be related to an excitotoxic mechanism.
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