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  • Title: Malignant melanoma of nasal cavity: report of 16 Japanese patients.
    Author: Nakaya M, Mochiki M, Takeuchi S, Yuge T, Nakao K, Nakamura N, Sugasawa M.
    Journal: Auris Nasus Larynx; 2004 Sep; 31(3):233-7. PubMed ID: 15364357.
    Abstract:
    BACKGROUND: Primary malignant melanoma of the nasal cavity is a rare disease that has a poor prognosis. There are significant racial differences in the incidence of melanomas in the nasal cavity. METHODS: Sixteen Japanese patients treated at the Hospital of Tokyo University were reviewed retrospectively. RESULTS: Fourteen patients were treated with surgery. Two patients received treatment with radiotherapy alone. Seven patients had microscopically negative surgical margins and seven patients had positive surgical margins. The 2- and 5-year actuarial survival rates for all patients were 63.6 and 31.8%, respectively. No statistically significant difference could be shown in the overall survival rate between patients with positive surgical margins and those with negative surgical margins. CONCLUSIONS: Clinical features of nasal melanoma in Japanese are not different from nasal melanoma in Caucasians. The negative surgical margins were not predictive of a better prognosis.
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