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  • Title: Affinity mass spectrometry from a tailored porous silicon surface.
    Author: Meng JC, Siuzdak G, Finn MG.
    Journal: Chem Commun (Camb); 2004 Sep 21; (18):2108-9. PubMed ID: 15367998.
    Abstract:
    The development of chemically stable porous silicon (pSi) materials for DIOS (Desorption/Ionization on Silicon) mass spectrometry, covalent linkers cleaved in the DIOS laser pulse, and efficient methods for bond formation to immobilized species, allows for on-chip affinity purification and mass detection.
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