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  • Title: [Advance in synthesis of ketolides, a new class of erythromycin derivatives].
    Author: Lei PS, Xu P, Liu L.
    Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2004 Aug; 26(4):467-73. PubMed ID: 15379279.
    Abstract:
    Drug-resistance has become a challenging clinical problem. Ketolides, a new class of erythromycin derivatives, have shown promising effectiveness in killing drug-resistant bacteria. This article reviews recent development in synthesis of ketolides, with focus on the modification and synthesis of some important positions on erythromycin A cycles.
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