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  • Title: Serum ascorbic acid concentrations in previously unsupplemented greyhounds after administration of a single dose of ascorbic acid intravenously or per os.
    Author: Scott KC, Hill RC, Lewis DD, Gronwall R, Sundstrom DA, Jones GL, Harper J.
    Journal: J Anim Physiol Anim Nutr (Berl); 2002 Aug; 86(7-8):222-8. PubMed ID: 15379908.
    Abstract:
    Plasma vitamin C concentrations (mean + SD) were measured after a large (1 g) dose of vitamin C was administered orally or intravenously to each of four trained greyhounds in a randomized cross-over design. Concentrations increased (p<0.05) for 2 h but returned to baseline by 6 h after supplementation. Peak concentrations were greater (p<0.01) after intravenous than oral administration (6.1+/-1.2 vs. 0.54+/-0.23 mg/dl). This suggests that vitamin C must be administered many times daily to maintain plasma concentrations above normal.
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