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  • Title: Sinonasal hemangiopericytomas. A clinicopathologic and DNA content study.
    Author: el-Naggar AK, Batsakis JG, Garcia GM, Luna ML, Goepfert H.
    Journal: Arch Otolaryngol Head Neck Surg; 1992 Feb; 118(2):134-7. PubMed ID: 1540341.
    Abstract:
    The clinicopathologic and the flow cytometric DNA characteristics of 14 patients with sinonasal hemangiopericytomas are presented. Patient and tumor characteristics were similar to previously published series. Flow cytometric analysis revealed a diploid DNA pattern and low S-phase in 13 neoplasmas and an aneuploid DNA pattern with relatively high S-phase in one. Histopathologically, all diploid and low S-phase neoplasms displayed relatively uniform cellular features and low mitotic counts. All patients are alive and free of disease; one is still alive after a single recurrence. Our data suggest that sinonasal hemangiopericytomas are low-grade neoplasms as evidenced by their histomorphology and their DNA content. Recurrences are delayed and can be controlled.
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