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  • Title: Self-association of kangaroo and chicken insulins, chicken despentapeptide insulin and deamidated insulin.
    Author: Jeffrey PD, Treacy GB.
    Journal: Biochim Biophys Acta; 1992 Feb 13; 1119(1):107-10. PubMed ID: 1540628.
    Abstract:
    Intact and modified metal-free insulins from kangaroo, chicken and pig have been purified by HPLC and studied by equilibrium sedimentation at pH 7. The aggregation of deamidated pig insulin is lowered significantly, consistent with its modified electrostatic charge. Native kangaroo and chicken insulins self-associate to the same extent as pig and cow insulins under these conditions. Despentapeptide chicken insulin does not self-associate at pH 7.
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