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  • Title: Current approaches and perspectives in human keratinocyte-based gene therapies.
    Author: Del Rio M, Gache Y, Jorcano JL, Meneguzzi G, Larcher F.
    Journal: Gene Ther; 2004 Oct; 11 Suppl 1():S57-63. PubMed ID: 15454958.
    Abstract:
    Inherited and acquired disorders are liable to treatment with somatic gene therapy. The skin, and in particular epidermal cells, are particularly suited to genetic manipulation and follow-up of therapeutic effects. Cutaneous gene therapy may be effective for skin defects and systemic abnormalities. The robust basic and preclinical data available today would support the application of keratinocyte-based gene therapy to patients.
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