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  • Title: Genetic diversity of sapovirus in fecal specimens from infants and children with acute gastroenteritis in Pakistan.
    Author: Phan TG, Okame M, Nguyen TA, Nishio O, Okitsu S, Ushijima H.
    Journal: Arch Virol; 2005 Feb; 150(2):371-7. PubMed ID: 15480859.
    Abstract:
    A total of 517 fecal specimens collected from infants and children with acute gastroenteritis in Karachi city, Pakistan during 1990-1994 were examined for the presence of sapovirus by RT-PCR and sequence analysis methods. Sapovirus was identified in 17 of 517 (3.2%) specimens. Sapovirus was further clustered into three distinct genogroups (I, II and IV) and these presented 70.6%, 23.5% and 5.9%, respectively. Our results clearly indicated that sapovirus could be classified into 7 GI and 4 GII genotypes. It was noteworthy to point out that sapovirus detected among Pakistani infants and children with acute gastroenteritis demonstrated the great genetic diversity and presented novel sapovirus genotypes.
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