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  • Title: Structurally simplified macrolactone analogues of halichondrin B.
    Author: Seletsky BM, Wang Y, Hawkins LD, Palme MH, Habgood GJ, DiPietro LV, Towle MJ, Salvato KA, Wels BF, Aalfs KK, Kishi Y, Littlefield BA, Yu MJ.
    Journal: Bioorg Med Chem Lett; 2004 Nov 15; 14(22):5547-50. PubMed ID: 15482921.
    Abstract:
    A structurally simplified macrolactone analogue of halichondrin B was identified that retains the potent cell growth inhibitory activity of the natural product in vitro.
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