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  • Title: Aripiprazole and neuroleptic malignant syndrome.
    Author: Chakraborty N, Johnston T.
    Journal: Int Clin Psychopharmacol; 2004 Nov; 19(6):351-3. PubMed ID: 15486522.
    Abstract:
    Aripiprazole, an atypical antipsychotic with a novel method of action, has only recently been awarded a license in the UK. We report our first patient to receive this drug, who had treatment-resistant schizophrenia and developed neuroleptic malignant syndrome (NMS) with aripiprazole. To our knowledge, this is the first published case report involving aripiprazole and NMS in a potentially fatal medical emergency. Further experience with this drug should indicate whether this is an isolated case (as described with other atypical antipsychotics) or constitutes a more serious risk than that suggested by the relatively beneficial therapeutic profile described in the literature to date.
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