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  • Title: Molecular determinants of Listeria monocytogenes virulence.
    Author: Dussurget O, Pizarro-Cerda J, Cossart P.
    Journal: Annu Rev Microbiol; 2004; 58():587-610. PubMed ID: 15487949.
    Abstract:
    Listeria monocytogenes is the etiological agent of listeriosis, a severe human foodborne infection characterized by gastroenteritis, meningitis, encephalitis, abortions, and perinatal infections. This gram-positive bacterium is a facultative intracellular pathogen that induces its own uptake into nonphagocytic cells and spreads from cell to cell using an actin-based motility process. This review covers both well-established and recent advances in the characterization of L. monocytogenes virulence determinants and their role in the pathophysiology of listeriosis.
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