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  • Title: Mortality due to constipation and short-segment Hirschsprung's disease.
    Author: Singh SJ, Arbuckle S, Little D, Manglick MP, Cass D.
    Journal: Pediatr Surg Int; 2004 Dec; 20(11-12):889-91. PubMed ID: 15490194.
    Abstract:
    We report a case of mortality secondary to constipation. A 12-year-old child with a history of constipation from the age of 9 years presented in moribund condition with intestinal obstruction secondary to idiopathic constipation. He underwent laparotomy and died within 24 h of operation. At postmortem there was no evidence of abnormalities of the enteric nervous system. A 2nd case of early neonatal death from Hirschsprung's disease is presented to demonstrate that short-segment aganglionosis can be detected at postmortem. Enterocolitis can rapidly progress and be fatal in short-segment Hirschsprung's disease.
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