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  • Title: Acute promyelocytic leukemia and HIV-1 infection: case report and review of the literature.
    Author: Kudva GC, Maliekel K, Richart JM, Batanian JR, Grosso LE, Sokol-Anderson M, Petruska PJ.
    Journal: Am J Hematol; 2004 Nov; 77(3):287-90. PubMed ID: 15495246.
    Abstract:
    We report a 27-year-old man with HIV-1 infection who developed acute promyelocytic leukemia (APL) with a novel complex three-way chromosomal translocation t(15;16;17). Induction of remission and consolidation with all-trans-retinoic acid (ATRA)- and anthracycline-based chemotherapy was followed by maintenance therapy consisting of ATRA, 6-mercaptopurine (6-MP), and methotrexate (MTX). Highly active antiretroviral therapy (HAART) was continued with brief interruptions. He remains in complete remission 40 months after diagnosis.
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