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  • Title: A model for the oscillatory motion of single dynein molecules.
    Author: Goedecke DM, Elston TC.
    Journal: J Theor Biol; 2005 Jan 07; 232(1):27-39. PubMed ID: 15498590.
    Abstract:
    Axonemal dynein is the molecular motor responsible for the rhythmic beating of eukaryotic cilia and flagella. An individual axonemal dynein molecule is capable of both unidirectional and oscillatory motion along a microtubule (Nature 393 (1998) 711). We propose a model which links the physical motion of a two-headed dynein molecule to its ATP hydrolysis cycle, and which exhibits both processive and oscillatory behaviors. A mathematical analysis of the model is used to make experimentally testable predictions.
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