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  • Title: Liver biopsy complicated by hemorrhage in a patient with ARC syndrome.
    Author: Hayes JA, Kahr WH, Lo B, Macpherson BA.
    Journal: Paediatr Anaesth; 2004 Nov; 14(11):960-3. PubMed ID: 15500499.
    Abstract:
    ARC syndrome is a rare disorder consisting of arthrogryposis, renal tubular acidosis and cholestatic liver disease. We report the case of a 5-week-old patient who underwent a percutaneous liver biopsy complicated by hemorrhage, and was subsequently diagnosed with ARC syndrome. A review of the literature demonstrates that these patients are at increased risk of bleeding caused by platelet dysfunction. The evaluation and management of unexpected hemorrhage in pediatric patients as a result of undiagnosed congenital bleeding problems is discussed.
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