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  • Title: [The model of height prognosis in children with growth hormone deficiency].
    Author: Kostecka L, Wasikowa R, Noczyńska A, Filipowski H.
    Journal: Endokrynol Diabetol Chor Przemiany Materii Wieku Rozw; 2004; 10(2):113-7. PubMed ID: 15504314.
    Abstract:
    The authors present a test for a prognosis of height in children with somatotropic hypofunction of the hypophysis treated with growth hormone. A statistic analysis of the height prognosis was performed on support of a model. With support of the examinations and the received results the following conclusions are proposed: 1. The prognosis of the final height in girls treated with growth hormone was statistically significantly lower than boys. 2. The longer the time of therapy with growth hormone the significantly higher the prognosis of height in these children. 3. In spite of 3 years period of growth hormone therapy even with the dose of 0.7 UJ rhGH the children do not achieve calculated prognosis of height. 4. Further examinations are necessary including more children with total or partial growth hormone deficiency with a longer duration of the observation. 5. An analysis of the final height in children after interruption of the growth hormone therapy at the age of 18 years is necessary.
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