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  • Title: Cutaneous nocardiosis complicating management of Crohn's disease with infliximab and prednisone.
    Author: Singh SM, Rau NV, Cohen LB, Harris H.
    Journal: CMAJ; 2004 Oct 26; 171(9):1063-4. PubMed ID: 15505269.
    Abstract:
    Infliximab is a chimeric anti-tumour necrosis factor-alpha antibody that is efficacious in treating Crohn's disease. However, its immunomodulatory properties increase susceptibility to opportunistic infections. We present a case of cutaneous Nocardia infection in a patient who was taking infliximab for Crohn's disease. The case illustrates the challenges in the diagnosis and management of this disease and serves as a reminder of the complications associated with the use of immunomodulatory agents.
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