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  • Title: Infliximab for the treatment of posterior uveitis with retinal neovascularization in Behçet disease.
    Author: Giansanti F, Barbera ML, Virgili G, Pieri B, Emmi L, Menchini U.
    Journal: Eur J Ophthalmol; 2004; 14(5):445-8. PubMed ID: 15506610.
    Abstract:
    PURPOSE: To report a case of posterior uveitis with retinal neovascularization in a patient with Behçet disease treated with infliximab. METHODS: A 50-year-old man with a history of recurrent relapses of ocular inflammation despite immunosuppressive therapy developed retinal neovascularization near the optic disk. The patient was treated with infliximab and followed up for 12 months. RESULTS: Retinal neovascularization regressed 8 months after the first anti-tumor necrosis factor (TNF) treatment and with six infusions of infliximab. The ocular inflammation resolved almost completely. CONCLUSIONS: The result suggests that anti-TNF therapy may be effective in the treatment of retinal neovascularization caused by panuveitis in Behçet disease.
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