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  • Title: [Extrapleural pneumonectomy of malignant pleural mesothelioma].
    Author: Yoon HE, Nonaka K, Fukuhara K, Ueshima H, Sugiura T, Kaneda H, Shimamoto S, Imakita M, Iwase K.
    Journal: Kyobu Geka; 2004 Oct; 57(11):1011-5. PubMed ID: 15510813.
    Abstract:
    We analyzed 7 patients with malignant pleural mesothelioma who underwent extrapleural pneumonectomy. Six men and a woman had a mean age of 65 years old. The postoperative mortality rate was 14% (1 death) and morbidity, 43% (3 cases). According to staging of International Mesothelioma Interest Group, 2 patients had stage I disease, 1 did stage II, 3 did stage III and 1 did stage IV. Local recurrences were found in 3 patients and metastasis in 2. In patients with local recurrences, 2 had irradiation with chemotherapy and 1, irradiation. In patients with recurrences of metastasis, 1 had chemotherapy and 1, supportive care. Seven patients with extrapleural pneumonectomy and 10 without surgery had median survivals of 16 months and 10 months, 1-year survival rates of 71% and 40% and 2-year survival rates of 57% and 0% respectively (p=0.071). Extrapleural pneumonectomy with adjuvant therapy could be effective treatment for malignant pleural mesothelioma.
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